Clinical Trial Will Test Use Of MRI To Improve Prostate Cancer Diagnosis And Management

MRI technology is an accurate tool that could better identify which patients should go through biopsy and enable targeted biopsy of only areas suspected of malignancy. The PRECISE trial, which is approximated to be completed in three years, will investigate the power of MRI to improve the diagnosis of medically important disease and reduce the requirement for prostate biopsies.

Currently, prostate malignancy is diagnosed by trans-rectal ultrasound (TRUS) -guided biopsy of the prostate, in most cases carrying out a Prostate Specific Antigen (PSA) test. TRUS-guided biopsy is associated with potential part results such as an infection and bleeding since it is not targeted, needing numerous biopsy samples (between 10 and 12) to establish an accurate reading. In addition, this current standard of care is not sensitive enough to be able to discriminate between high-risk and very low-risk changes in prostate cells, resulting in the over-diagnosis and over-treatment of many men, exacerbating the chance for side results. Dr. Lincoln Stein, Interim Scientific Director of the Ontario Institute for Cancer Research.

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Data management and evaluation for the trial will be conducted by the Ontario Clinical Oncology Group (OCOG) in the Escarpment Cancer Research Institute, a Hamilton Health McMaster, and Sciences University or college institute. Dr. Mark Levine, Director of OCOG. Dr. Stuart Edmonds, PCC’s vice-president of Research and Health Promotion. Dr. Klotz is your physician and researcher structured at the Sunnybrook Health Sciences Center in Toronto. He is also a professor at the University of Toronto and the Seat of the global world Urologic Oncology Federation. Last month he was invested as a Member of the Order of Canada.

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